R Jeremy Johnson Selected Research

Hydrolases

1/2021	Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C.
1/2020	Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae.
10/2017	Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity.
12/2016	Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW.
12/2014	Distinct substrate selectivity of a metabolic hydrolase from Mycobacterium tuberculosis.
4/2013	Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.

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R Jeremy Johnson Research Topics

Disease

4	Tuberculosis (Tuberculoses) 01/2021 - 12/2014
2	Infections 01/2019 - 12/2016
1	Neoplasms (Cancer) 01/2020
1	Acquired Immunodeficiency Syndrome (AIDS) 07/2014
1	Bacterial Infections (Bacterial Infection) 04/2013
1	Acute Erythroblastic Leukemia (Erythroleukemia) 04/2007

Drug/Important Bio-Agent (IBA)

6	HydrolasesIBA 01/2021 - 04/2013
5	Serine (L-Serine)FDA Link 01/2021 - 04/2013
2	Biological ProductsIBA 10/2017 - 12/2016
1	MetalsIBA 01/2021
1	XenobioticsIBA 01/2019
1	EstersIBA 01/2019
1	EsterasesIBA 01/2019
1	ProdrugsIBA 01/2019
1	ProteomeIBA 10/2017
1	Ethambutol (Myambutol)FDA LinkGeneric 10/2017
1	EnzymesIBA 12/2014
1	HIV ProteaseIBA 07/2014
1	Proteins (Proteins, Gene)FDA Link 04/2013
1	Ribonucleases (Ribonuclease)IBA 04/2007